Week 12 schedule with three practices and full media availability before Monday night's matchup against the Panthers.

Panthers vs. 49ers will broadcast nationally on ESPN/ABC in Week 12 of the 2025 season. Joe Buck (play-by-play commentator), Troy Aikman (color analyst), Lisa Salters (sideline reporter) and Laura Rutledge (sideline reporter) are on the call.

49ers vs. Panthers will be on "Monday Night Football" in Week 12, which will air nationally on both ABC and ESPN. Joe Buck (play-by-play) will be in the booth alongside Troy Aikman (analyst). The game will stream live on the ESPN app, along with Fubo, which offers a free trial.

When you looked at the 49ers’ schedule back in August, you probably circled this Week 13 trip to Cleveland as an easy road win. The Browns stink. They always stink. It’s part of the NFL’s natural order, like the sun rising or Tom Brady botching the broadcast call on a big third down.

A resilient 49ers team is welcoming the rest of the upcoming bye week after positioning themselves well for a postseason run with three straight wins.