IgA nephropathy often has no symptoms for years, but when they appear, they may include blood in the urine, flank pain, and swelling. The condition damages the kidney's glomeruli, which can lead to ...

Immunoglobulin A (IgA) nephropathy, also called Berger disease, occurs when IgA antibodies clump, damage kidney filters, and cause blood and protein in the urine. Liver disease is the most common ...

IgA Nephropathy (IgAN) is an autoimmune kidney disease. Without treatment, it can cause a variety of complications. Treatment focuses on disease management and slowing disease progression. Also known ...

Most cases of immunoglobulin A (IgA) nephropathy are sporadic (or idiopathic), occurring over time for reasons experts don't fully understand. Research suggests that genetic factors are involved in ...

Sibeprenlimab is approved for IgAN treatment, showing a 51.2% reduction in proteinuria in the VISIONARY trial. Administered subcutaneously every four weeks, it inhibits APRIL to reduce IgA levels.