Amplicon infection induces a cascade of innate responses that can result in tissue-dependent restriction of transgene expression. Amplicon-mediated transgene expression is at least partially silenced ...
Among the viral vectors, those derived from alphaviruses occupy a specialized niche. 9, 10 Semliki Forest Virus (SFV) and Sindbis Virus (SV) are the main two alphaviruses from which vectors have been ...