Chronic pain can be debilitating and frustrating, especially among aging adults. While physical remedies and treatments can provide some relief, experts have found that shifting one's mindset — or the ...

Pain and mood have a complicated relationship. Numerous studies show that low mood intensifies the experience of pain. Likewise, pain disorders develop more commonly in people with a history of ...

For the more than 50 million Americans living with chronic pain, the question has always been the same: why does it stay? A torn ligament heals. A surgical wound closes. Yet the pain persists, ...

Researchers have a better understanding of the nocebo effect and the neuroscience behind it all. Opposite of the better-known ...

Scientists have pinpointed Y1 receptor neurons in the brain that can override chronic pain signals when survival instincts like hunger or fear take precedence. Acting like a neural switchboard, these ...

When living with chronic pain, over time, the brain becomes hypersensitive to pain signals, which increases pain. Pain is a danger signal. When something happens, such as touching a hot surface or ...

Scientists have identified the brain circuit behind the nocebo effect, revealing how fear and negative expectations can make ...

Deep within the brain, scientists have uncovered a hidden “switch” that may decide whether pain fades away—or lingers for months or even years. Researchers found that a small, little-known region ...

Kendra Pierre-Louis: For Scientific American’s Science Quickly, I’m Kendra Pierre-Louis, in for Rachel Feltman. From stubbing your toe to dealing with the occasional headache or sore back, to ...

Researchers have long wondered why some people with chronic pain develop depression. yourphotopie/ Shutterstock Researchers have long been wondering why this happens – and what goes on in the brain.

A noninvasive treatment called high-intensity focused ultrasound helped relieve the shaking, stiffness and pain that accompany Parkinson’s disease.

Researchers at Carnegie Mellon are combining neuroimaging and technology to better understand pain in people with sickle cell disease, aiming for more compassionate care. Pain is a constant, complex ...