Cancer genomes are the result of diverse mutation processes that have often accumulated over decades. Scientists have analyzed the molecular evolution of tumors after exposure to mutagenic chemicals.

Mutations accumulated in mitochondrial DNA associated with aging were earlier believed to cause aging by decreasing the energy-producing function (mitochondrial respiratory function). In this study, ...

Gene editing technology allows to introduce and correct disease-linked mitochondrial DNA mutations in liver and skin cells In a step toward treating mitochondrial diseases, researchers in the ...

In a step toward treating mitochondrial diseases, researchers in the Netherlands have successfully edited harmful mutations in mitochondrial DNA using a genetic tool known as a base editor. The ...