That states of extreme positive energy balance and peripheral insulin resistance result in reproductive dysfunction is becoming increasingly clear. To investigate the response of reproductive tissues ...

(RTTNews) - Aardvark Therapeutics (AARD) reported positive preclinical results for ARD-201 in a diet-induced obesity (DIO) mouse model, indicating potential as an oral treatment for weight loss and ...

Announced class-leading data from diet-induced obesity (DIO) mouse model with NMRA-215, a potentially best-in-class, highly brain-penetrant, oral NLRP3 inhibitor, and expect to initiate Phase 1 study ...

13-week follow-up represents the longest data to-date demonstrating durable efficacy of RJVA-001 on weight and blood sugar in the diet-induced obesity (DIO) mouse model Company plans to use durable ...

This study is reported by the team of Professor Shuang-jiang Liu from Shandong University. The study reveals that the gut probiotic Christensenella tenuis significantly alleviates endotoxemia and ...

Schematic illustration of high temperature ameliorated high-fat diet-induced insulin resistance in SMT of DIO mice. HT, high temperature (40℃, 4 h); DIO, diet-induced obesity; HSF1, heat shock factor ...