Researchers at Baylor College of Medicine and collaborating institutions report in the journal Nature Communications how a mutation in the enzyme SKD3 can cause a form of a genetic disease known as ...
Enzymes originally evolved in high-temperature environments and later adapted to lower temperatures as Earth cooled. Scientists discovered that a key shift in enzyme function occurred over ...
Researchers discovered that a tiny structural feature of the enzyme GPX4 helps keep neurons safe. A rare mutation removes this protection, allowing harmful molecules to damage cell membranes and ...
In nature, evolution takes years to sculpt new traits. In the lab, scientists hope to achieve this feat much faster: Being able to evolve proteins with enhanced or novel functions has important ...
An enzyme that defends human cells against viruses can help drive cancer evolution towards greater malignancy by causing myriad mutations in cancer cells, according to a study led by investigators at ...
Scientists have developed a novel approach to modifying enzymes to improve functionality. They designed a new algorithm to make multiple changes to an enzyme sequence at once as compared to the ...
The results revealed a clear sequence. Enzymes predating cannabis showed no ability to process CBGA. The first enzyme unique ...
Cannabis produces a complex suite of bioactive compounds, including tetrahydrocannabinol (THC) and cannabidiol (CBD), but how ...
Kyle Miller and his team discovered a potential new target for drug therapies: structures in our DNA called R-loops. A human cancer cell that overexpresses the enzyme APOBEC3B (left) has fewer R-loops ...
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has had a profound impact on society and the economy worldwide. Since its emergence at the end of 2019, extensive research has been ...