In 2020, news headlines repeated John Moult’s words at the end of a stunning competition: Artificial intelligence had “solved” a long-standing grand challenge in biology, protein structure prediction.
On Wednesday, the Nobel Committee announced that it had awarded the Nobel Prize in chemistry to researchers who pioneered major breakthroughs in computational chemistry. These include two researchers ...
One of the hallmarks of Alzheimer's disease is the clumping of proteins called Tau, which form tangled fibrils in the brain.
Computational models show that even subtle modifications in the synaptic protein CaMKII completely alter the resulting protein structures. Given how the formation and stability of these structures ...
Researchers have identified the specific structural loops in G-quadruplex DNA that allow it to act as a chaperone, preventing ...
Protein molecules can have complicated structures that dictate their functions. Christoph Burgstedt/Science Photo Library via Getty Images Although the Nobel Prizes in physics and chemistry are ...
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New framework leverages 3D protein structures for systems-level analysis of cancer mutations
A study from Cornell researchers could enable a quantum leap forward in identifying and deciphering cancer-driving genetic mutations, the first step in developing effective therapeutics. Cells become ...
The first full-length structures of two heat shock chaperone proteins in a complex reveal the key structural region regulating their function, according to a new study from St. Jude Children's ...
In 2020, news headlines repeated John Moult’s words at the end of a stunning competition: Artificial intelligence had “solved” a long-standing grand challenge in biology, protein structure prediction.
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