Here's a list of the best Mississippi River cruise itineraries you can book in ... Highlights of the weeklong voyage include a visit to the historic Houmas House Estate and Gardens in Darrow ...

As you sail, you'll encounter stunning landscapes, from the majestic Cascade Range to the serene vineyards of Washington. The ...

American Cruise Lines has announced its most comprehensive Mississippi river season for 2025. There will be five riverboats sailing 12+ itineraries on the river and its tributaries year-round. The ...

Mississippi River Cruises The Mississippi River, often referred to as the backbone of America, offers a rich tapestry of ...

Opt for American Cruise Lines’ seven-night Historic Mississippi River Cruise if you really want to immerse yourself in the Deep South. The roundtrip begins in New Orleans, where you can ...

8-Day Historic Mississippi River Cruise (roundtrip from New Orleans, LA) 9-Day Lower Mississippi River Cruise (Memphis, TN to New Orleans, LA) 9-Day Upper Mississippi River Cruise (St. Louis ...

and even a National Parks cruise visiting Great Smoky Mountains National Park. 8-Day Historic Mississippi River Cruise (roundtrip from New Orleans, LA) 9-Day Lower Mississippi River Cruise (Memphis, ...