In the 'off' state, the Lac inhibitor represses the lac operon, which prevents expression of the Tet repressor and the target gene. Additionally, a short hairpin RNA (shRNA) ...

The Scientist's content tagged with: Lac Operon. Agilent BioTek Cytation C10 Confocal Imaging Reader. From confocal, widefield, and live cell imaging to multimode reading, the Agilent BioTek Cytation ...

The lac operon is always expressed, even in the absence of lactose. I s (super repressor) Repressor cannot bind lactose; thus, it cannot be released from the operator site.

Monod and Jacob's lac operon turned out to be the first of many bacterial operons. But by the late 1960s, it was clear that operons weren't the biological norm.