The STING protein, known for helping cells fight viral infections by generating inflammation, also appears to function as a ...

It has a range of preclinical-stage projects that aim to harness lysosomes’ ability to clear ... rare disease that targets the TRPML1 ion channel. It also has slightly earlier-stage programmes ...

Wang et al. show the recruitment of the lipid channel protein VPS13C and formation of VPS13C-dependent contacts between endoplasmic reticulum and lysosomes after lysosomal damage. The function and ...