One distinct feature of transcription factors is that they have DNA-binding domains that give them the ability to bind to specific sequences of DNA called enhancer or promoter sequences.

Promoter sequences are typically located directly upstream or at the 5' end of the transcription initiation site. RNA polymerase and the necessary transcription factors bind to the promoter ...

TFIID enables RNA polymerase II promoter-proximal pausing ... Taatjes, DJ; Young, RA. Transcription factors activate genes through the phase separation capacity of their activation domains. Cell 2018, ...

The numbers of the principal regulatory elements present in insulin promoters are listed. Given the complexity and uncertainty of predicting the transcriptional outcome of mutations within ...

This may shed light on the proteins that interact with promoters and induce transcription." Campbell, co-curator of the database, added that "the identification of transcription factors that bind ...

It is essential that new human ß-cell lines be developed and widely distributed in order that physiologically and medically relevant studies on the human insulin promoter can be carried out.