Proteins are the end products of the decoding process that starts with the information in cellular DNA. As workhorses of the cell, proteins compose structural and motor elements in the cell, and they ...

The human genome comprises both canonical protein-coding genes and a vast number of non-canonical coding regions, yet the translation products of the latter remain largely underexplored. Now, the ...

Inspired by the simple mechanism of a seesaw—when one side goes up, the other side goes down—researchers asked an intriguing question: Could a single molecule switch between two different roles like a ...

Researchers have unveiled LoL-align, a probabilistic protein structure alignment algorithm that outperforms TM-align and Dali ...

Backed by $52M in federal funding, a Hopkins-led team will build an AI model to identify how shape-shifting proteins misfold ...

Some cells, such as immune cells, are highly mobile—they constantly remodel their shape, migrate toward a wound that needs to be closed or chase down bacteria in the bloodstream. This mobility is ...

Newswise — Imagine a robot with fingers so flexible they can grasp an object the same way a human hand does. That’s the goal of soft robotics, but a major obstacle in advancing the field has been ...

On Wednesday, the Nobel Committee announced that it had awarded the Nobel Prize in chemistry to researchers who pioneered major breakthroughs in computational chemistry. These include two researchers ...

Researchers have developed ProtSAVI, an R-based dashboard that combines protein structure analysis with ACMG/AMP criteria to ...

Carbohydrates are polyhydroxy aldehydes or ketones, or substances that hydrolyze to yield these compounds. Their classification is based on the degree of polymerization, with monosaccharides being the ...

In genetics, one harmful variant can be enough to cause disease—but two can make it far more severe. One notable example is KJ, an infant diagnosed with a rare urea cycle disorder with a grim ...