Elevated TRMT10C protein levels in Alzheimer's disease result in methylation of mitochondrial mRNA and subsequently in the suppression of the synthesis of a subunit protein of complex I of the ...

A groundbreaking study has shed light on the critical role of a tRNA methylation enzyme, TRMT10A, in supporting brain function. The findings reveal how the absence of TRMT10A leads to a reduction in ...

This review is designed by Dr. Junhong Han and written by his postdoctoral researcher Dr. Lei Qiu and PhD student Qian Jing (Research Laboratory of Tumor Epigenetics and Genomics, West China Hospital, ...

The highly infectious nature of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is largely due to its affinity for mutations that continue to evolve and emerge throughout the current ...

A chemical modification in the HIV-1 RNA genome whose function has been a matter of scientific debate is now confirmed to be key to the virus's ability to survive and thrive after infecting host cells ...