The treatment of long benign oesophageal strictures remains a clinical challenge. We present a novel endoscopic technique ...

Background and aims Quantifying systemic inflammation (SI) in acutely decompensated cirrhosis (ADC) is of major importance ...

Background Current treatments with tyrosine kinase inhibitors and immune checkpoint inhibitors have limited efficacy for ...

We thank Dr Yang and colleagues for their interest in the HELIOS trial and their thoughtful appraisal of our findings.1 2 Yang et al highlight the possibility that heterogeneity in endoscopist ...

Background Endoscopic procedures are a notable source of medical waste, contributing significantly to environmental pollution. Prior studies report 0.5–3.0 kg of waste per procedure—compared with just ...

Background Determining optimal management of colorectal polyps in patients with limited life expectancy of under 10 years can be difficult, due to challenges balancing an uncertain natural history of ...

Background Injured or reactive biliary epithelial cells participate in most chronic liver injuries in a process referred to as ductular reaction, which involves multicellular interactions with marked ...

Background Recommendations for the first postpolypectomy surveillance colonoscopy (SC1), based on stratifying postpolypectomy colorectal cancer (CRC) risk, are well established. Limited data inform ...

Figure 2 NaBu combined with anti-PD-1 modulates the cytotoxic subpopulation mainly through the GNLY + CD8 + T cell subset to improve immunotherapy. (A) Uniform manifold approximation and projection ...

Correspondence to Dr M Lisa Zhang, Department of Pathology, Massachusetts General Hospital, Boston, Massachusetts, 02114, USA; mlzhang{at}mgh.harvard.edu Objective Elevated pancreatic cyst fluid ...

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Systemic therapy represents the standard of care treatment for patients with advanced hepatocellular carcinoma (HCC). Given the increased risk of death from cirrhosis-related complications in patients ...