Purpose Sotatercept, an activin signalling inhibitor approved in March 2024 for pulmonary arterial hypertension (PAH), ...

Background Hospitalisation with acute heart failure (AHF) carries a high risk of death, and those surviving to discharge ...

Background Aortogenic stroke is an important subtype of embolic strokes, yet lacks a diagnostic method for proactive ...

Background Biochemical markers of inflammation, coagulation and myocardial stress have been associated with both prevalent ...

Background The long-term effects of myocarditis following COVID-19 vaccination on cardiac function and symptoms remain unclear. Purpose To assess the long-term effects of myocarditis following ...

Objective To update the Cochrane systematic review of exercise-based cardiac rehabilitation (CR) for heart failure. Methods A systematic review and meta-analysis of randomised controlled trials was ...

Myo-inositol, also known as inositol (cyclohexanehexol), is a cyclic carbohydrate with six hydroxyl groups.1 For a long time, it was considered a B vitamin (vitamin B 8). However, it is not considered ...

Objectives To determine contemporary population estimates of the prevalence of cardiac permanent pacemaker (PPM) insertions. Methods A population-based observational study using linked hospital ...

Objectives To explore changes over time in the 30-day mortality rate for paediatric cardiac surgery and to understand the role of attendant changes in the case mix. Methods, setting and participants ...

Objective Blood pressure (BP) control outside pregnancy is associated with a reduction in adverse cardiovascular events, and in pregnancy with improved outcomes. Outside pregnancy, there is evidence β ...

Objective Takotsubo syndrome (TTS) is an acute heart failure syndrome which resembles acute coronary syndrome (ACS) at presentation. Differentiation requires coronary angiography, but where this does ...

Aim In the UK, pharmacological management of patients with heart failure (HF) occurs predominantly in general practice. Using data from the Clinical Practice Research Datalink, we examined the ...