Rubio said he could not predict if Trump would succeed in buying Greenland from Denmark or restoring American authority over the Panama Canal while he is in office.

Newly inaugurated U.S. President Donald Trump is pushing to "take back" the Panama Canal, the world's second busiest interoceanic waterway.

Panama's President Jose Raul Mulino has ruled out negotiations with the US over ownership of the Panama Canal as he prepares to Marco Rubio.

In recent weeks, when he was President-elect Donald Trump publicly said that Panama should return the Panama Canal to the United States, and he would not rule out using military force to reclaim it. At his presidential Inauguration on Monday Trump doubled down on saying that his new administration was going to take back the canal.

When Marco Rubio arrives in Latin America this weekend on his first foreign trip as Donald Trump's secretary of state, he'll find a region reeling from the new administration's shock-and-awe approach to diplomacy.

Stephanie: In response to Trump’s inauguration speech, Panama President José Raúl Mulino said that “ the canal is and will remain Panama’s .” As you noted, Trump has already floated the idea of using military force to retake the canal. Do you think this could actually come to pass?

Russia warned President Trump on Tuesday against seizing the Panama Canal, after he reiterated his intent to take control of the strategic waterway in his second inaugural address Monday.