After allowing time for gene expression, the cells are assayed for reporter mRNA, the reporter protein itself ... dynamic range of response (over several orders of magnitude). The assay should be ...

Numerous widely used chemicals induce genetic and epigenetic alterations implicated in various diseases, including cancer.

Chemicals used in different applications induce genetic and epigenetic aberrations implicated in various diseases, including ...

CAR-T Target Luciferase Reporter ... cell for in vitro killing assay by CD19, CD20, or HER2 CAR-T cells. These luciferase expressing cell lines were derived from parental lines by transduction with ...

Gene-editing ... An isogenic cell line was created to model cancer patients with the echinoderm microtubule-associated protein-like 4 (EML4)-anaplastic lymphoma kinase (ALK) fusion oncogene ...