For one, microglia hovering around plaques—the type that express the most TREM2—reportedly become desensitized to stimulation ...

Examples of organelles include the nucleus, the endoplasmic reticulum, the Golgi, mitochondria, vacuoles or lysosomes, and chloroplasts (in plants). The mitochondrial unfolded protein response ...

Alzheimer's disease is one of the world’s most prevalent brain disorders, being extremely difficult to treat. Alzheimer's ...

For example, many fetuses ... Lysosomal storage disorders. Lysosomes are spaces inside cells that break down waste products of metabolism. Various enzyme deficiencies inside lysosomes can result ...

A recent study reveals that regular cold water swimming can positively alter cellular stress responses. Immersing healthy young men in cold water dail ...

for example, specific HER2 antibodies," explains Dr. Aura Muntasell, researcher from the Immunity and Infection Research Group of the Hospital del Mar Research Institute and lecturer in the ...

The biotech is focusing on precision, small-molecule medicines that work via a process known as cellular clearance by activating the lysosome, sometimes referred to as the cell’s recycling and ...

Get Instant Summarized Text (Gist) Emotional overattachment to social media is linked to increased severity of mental health symptoms in youth treated for depression, anxiety, and suicidal ...

ADCs in Preclinical Development for the Treatment of B-cell Malignancies With the evolving clinical data demonstrating the feasibility of the ADC platform in hematologic malignancies, the ...

The oncogene LAPTM4B (encoding lysosome-associated protein transmembrane-4β), first cloned in hepatocellular carcinoma cells, is located on chromosome 8q22.1 and encodes two isoforms, LAPTM4B-35 and ...