Immunoglobulin G's overlooked hinge turns out to be a structural control hub

The lower hinge of immunoglobulin G (IgG), an overlooked part of the antibody, acts as a structural and functional control hub, according to a study by researchers at Science Tokyo. Deleting a single ...

A 'Highway' for Protein Structure Big Data Alignment Opens... Revolutionizing Disease Research [Reading Science]

A domestic research team has developed an ultra-fast analysis technology capable of simultaneously tracking the evolutionary process of proteins ...
Business Wire

OpenFold Consortium Releases Preview of OpenFold3: An Open-Source Foundation Model for Structure Prediction of Proteins, Nucleic Acids, and Drugs

DAVIS, Calif.--(BUSINESS WIRE)--The OpenFold Consortium, a leading nonprofit artificial intelligence (AI) research consortium, today announced a preview release of OpenFold3, an open-source deep ...
IEEE

Protein-Binding RNA Prediction Based on Integrated Sequence-Structure-Function Pre-Training

Abstract: RNA binding proteins (RBPs) play a crucial role in regulating biological functions through their interactions with specific RNAs, significantly impacting various life processes.
IEEE

PGDTA: Predicting Drug-Target Affinity Using Three-Dimensional Structure of Protein Pocket and Graph Neural Network

Abstract: Drug-Target Affinity (DTA) prediction plays a crucial role in drug discovery, and accurate DTA prediction can significantly reduce the cost of drug development. While most studies focus on ...
Seeking Alpha

OptimumBank Holdings, Inc. Announces Capital Structure Enhancements Reflecting Strong Institutional and Insider Alignment

Fort Lauderdale, Florida--(Newsfile Corp. - January 5, 2026) - OptimumBank Holdings, Inc. (OPHC) (the "Company") is pleased to provide a year-end update on the successful completion of a comprehensive ...