Head coach Kyle Shanahan told reporters at a Monday press conference that running back Isaac Guerendo is going to miss a ...

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49ers coach Kyle Shanahan said Monday that Guerendo (shoulder) is expected to miss a couple weeks, Matt Maiocco of NBC Sports Bay Area reports.

It’s time for the San Francisco 49ers to reevaluate the running back position. The depth chart order behind Christian ...

San Francisco 49ers running back Christian McCaffrey explained why he sometimes feels uneasy sleeping in a hotel room amid ...

Guerendo had an early departure from practice Saturday due to an apparent shoulder injury, Jennifer Lee Chan of NBC Sports Bay Area reports.

Injuries forced running back Isaac Guerendo and fullback Kyle Juszczyk out of Saturday’s practice at 49ers training camp.

San Francisco 49ers running back Isaac Guerendo (shoulder) is expected to miss a couple of weeks, according to Matt Maiocco ...

What’s changed: Healthy since early in the offseason, McCaffrey predictably earned raves for his spring work. Coach Kyle ...

The 49ers have to come to grips that this running back is injury-prone and cannot be relied upon when the season begins.