1Molecular Pharmacology of Malignant Diseases, Graduate School of Pharmaceutical Sciences, ...
1Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, ...
Abstract. Antibody-drug conjugates (ADCs) enable the specific targeting of a potent cytotoxic drug to cancer cells expressing a select antigen via the release of the cytotoxin covalently linked to a ...
School of Pharmaceutical Sciences - USM, Penang, Malaysia.
Abstract. Background: Lung cancer is the most lethal malignancy worldwide and urgently requires effective early detection strategies. Current non-invasive approaches based on plasma cell-free DNA ...
Bold Therapeutics Inc, Vancouver, British Columbia, Canada.
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Abstract. Breast cancers with high expression of estrogen receptor (ER), progesterone receptor (PR), or Human Epidermal Growth Factor Receptor 2 (HER2) have benefited dramatically from ...
Abstract. Targeting ligands play a critical role in radiopharmaceuticals for cancer diagnosis and therapy. Due to their excellent binding affinity and specificity, peptides have been widely used to ...
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Abstract. Bispecific antibodies and chimeric antigen receptor (CAR) T-cells are some of the most potent cancer immunotherapeutics in clinical use, yet most cancers remain poorly targetable.
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