Purpose Sotatercept, an activin signalling inhibitor approved in March 2024 for pulmonary arterial hypertension (PAH), ...

Background Hospitalisation with acute heart failure (AHF) carries a high risk of death, and those surviving to discharge ...

Background Aortogenic stroke is an important subtype of embolic strokes, yet lacks a diagnostic method for proactive ...

Background Biochemical markers of inflammation, coagulation and myocardial stress have been associated with both prevalent ...

Objective To update the Cochrane systematic review of exercise-based cardiac rehabilitation (CR) for heart failure. Methods A systematic review and meta-analysis of randomised controlled trials was ...

Background The long-term effects of myocarditis following COVID-19 vaccination on cardiac function and symptoms remain unclear. Purpose To assess the long-term effects of myocarditis following ...

Myo-inositol, also known as inositol (cyclohexanehexol), is a cyclic carbohydrate with six hydroxyl groups.1 For a long time, it was considered a B vitamin (vitamin B 8). However, it is not considered ...

Objectives To explore changes over time in the 30-day mortality rate for paediatric cardiac surgery and to understand the role of attendant changes in the case mix. Methods, setting and participants ...

Objectives To determine contemporary population estimates of the prevalence of cardiac permanent pacemaker (PPM) insertions. Methods A population-based observational study using linked hospital ...

Background Hypoxic pulmonary vasoconstriction leads to an increase in pulmonary artery pressure (PAP) and potentially right heart failure in healthy individuals and patients with respiratory diseases.

Aim In the UK, pharmacological management of patients with heart failure (HF) occurs predominantly in general practice. Using data from the Clinical Practice Research Datalink, we examined the ...

Objectives Previous studies have reported beneficial effects of perioperative music on patients’ anxiety and pain. We performed a systematic review and meta-analysis of randomised controlled trials ...