This study presents a valuable finding on the direct cytotoxic effects of DuoHexaBody-CD37 in diffuse large B-cell lymphoma, mediated via SHP-1 activation and antibody clustering, independent of ...

MedlinePlus. Changing your sleep habits. Food and Drug Administration. Do cell phones pose a health hazard?. Centers for Disease Control and Prevention. Facts about cell phones and your health.

“So why don’t we test rape kits that also have DNA that is equally important to the criminal justice process?” The organization recommends several key reforms for states to adopt: the ...

“We meticulously designed all aspects of ALX2004 – the antibody backbone, linker and payload – to optimize the targeted delivery of a powerful chemotherapy payload to tumor cells while minimizing ...

Axi-cel, tisa-cel, and brexu-cel were found comparable to other cellular therapy experiences for patients with B-cell malignancies in real-world data. The use of 3 CD19-directed CAR T-cell therapies ...

To overcome these limitations, we engineered oncolytic viruses co-expressing neoantigens and neoantigen-binding major histocompatibility complex (MHC) molecules to force ectopic delivery of ...

A prominent feature of IBM on microscopy is highly differentiated effector CD8+ cytotoxic T (Tc) cells invading non-necrotic myofibers [1]. These Tc cells, known to be relatively resistant to ...

The FPKM values of T-cell-related genes, including CD3g, CD4, and CD8a, and B-cell-related genes, including Pax5 and CD19, were <1 in the kidney and liver but >1 in the lungs, indicating that T/B cell ...

Department of Pharmacology and Toxicology (O.T.H., N.C., E.D., L.M.A., D.W., K.W., T.W.T., E.H.C., S.B., G.W.B., D.C.C., B.L.), University of Mississippi Medical ...

Department of Pharmacology and Toxicology, University of Mississippi Medical Center, Jackson. (N.C., E.D., L.M.A., D.W., K.W., T.T., E.H.C., S.B., G.W.B., D.C.C., B.L ...

1Children’s Research Institute and the Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, Texas. 10Howard Hughes Medical Institute, UT Southwestern Medical Center, ...

Poor physical performance in patients with non-Hodgkin lymphoma receiving CAR T-cell therapy was linked to worse survival and increased risk of neurotoxicity in a cohort study.