A cutting-edge approach to immunotherapy shows that forcing cancer cells to die through necroptosis can dramatically boost the body's anti-tumor defenses. By combining three existing drugs, scientists ...

Thomas Yau and colleagues’ CheckMate 9DW trial has yielded unprecedented results, with nivolumab plus ipilimumab reaching an overall response rate of 36%, a median progression-free survival of 9·1 ...

We thank Akhil Santhosh and Nihanthy D Sreenath and Liting Zhang and colleagues for their interest in our trial. The CheckMate 9DW trial showed clinically significant overall survival benefit for ...

Scientists have uncovered an unexpected function for a crucial protein involved in cell division. Reported in two consecutive publications, the finding challenges long-accepted models and standard ...

Researchers uncovered a powerful weakness in lung cancer by shutting down a protein that helps tumors survive stress. When this protein, FSP1, was blocked, lung tumors in mice shrank dramatically, ...

Guillermo del Toro's take on Victor Frankenstein (Oscar Isaac) in his and Netflix's Frankenstein differs from the movie ...