Numerous widely used chemicals induce genetic and epigenetic alterations implicated in various diseases, including cancer.

Further, HS is not a determinant of HSV-1 entry pathway, nor does HS enhance pH-neutral fusion in a cell–cell fusion assay in the presence of gC. Notably, gC-null HSV-1 is rapidly internalized by ...

The company was originally formed with a primary focus on the research of emerging classes of medicines like cell and gene therapies. The startup came out the gate with cash not only from Battelle ...

The emphasis on transcription factors, cell surface, and secreted proteins provides valuable insights into the intricate gene regulatory networks underpinning neural tissue patterning. Analysis of a ...

Figure 3: Optimization of an on-bead affinity-based assay for the determination of a biasing peptide sequence. We also tested these peptides for inhibition of gp41-mediated cell fusion activity in ...

Reproducibility of cell-based assays is one of the key points when it comes to reliability of experimental data. Despite of choosing the appropriate assay type, there are many more factors to be ...

After allowing time for gene expression, the cells are assayed for reporter mRNA, the reporter protein itself ... dynamic range of response (over several orders of magnitude). The assay should be ...

CRISPR/Cas9 gene-editing is an innovative technology that enables precise genome editing to treat certain genetic diseases by targeting and altering specific DNA sequences. CASGEVY is a one-time ...

Department of Molecular and Environmental Biotechnology, Faculty of Biology and Biotechnology, University of Science, Ho Chi Minh City 700000, Vietnam Vietnam National University, Ho Chi Minh City ...

Cell- and gene-therapy-focused ElevateBio has let go of 17% of staffers as part of the company’s second layoff round since raising $401 million nearly two years ago. “To ensure long-term ...

Currently, there are only two cell and gene therapies (CGTs) within the gastroenterology market. (Image Credits: Pixabay) The global cell and gene therapy (CGT) market is poised for exceptional ...