The New York Times: Mutated DNA Restored To Normal In Gene Therapy Advance Researchers have corrected a disease-causing gene mutation with a single infusion carrying a treatment that precisely ...

Acquired DNA mutations found in the SERPINA1 gene can protect liver cells from damage in patients with alpha-1 antitrypsin deficiency, new research shows. Alpha-1 antitrypsin deficiency (A1AD ...

By Gina Kolata Researchers have corrected a disease-causing gene mutation with a single infusion ... C and T — in DNA. The effect was to change an incorrect DNA letter to the right one.

Scientists found that rapidly evolving DNA regions, known as human accelerated regions (HARs), help human neurons form complex networks, contributing to higher brain function but possibly increasing ...

In the past 13 years, more than 100 point mutations and innumerable rearrangements of mitochondrial DNA (mtDNA) have been associated with human mitochondrial disease. In the past five years ...

Each DNA strand contains many genes. All cancers begin when DNA mutations, or changes, cause cells to divide and grow out of control. But this is different from hereditary cancer. Hereditary or ...

Evidence is provided to show that it is not simply the fact that males have more cell divisions in the germline, but instead, most of the mutations arise from a different balance of DNA damage vs. DNA ...

DNA replication errors that persist as mismatch mutations make up the molecular fingerprint of mismatch repair (MMR)-deficient tumors and convey them with resistance to standard therapy. Using ...