A study led by Prof. Liu Feng from the Institute of Zoology of the Chinese Academy of Sciences has identified a crucial role ...

Intricate regulation of gene expression is important for execution of biology processes. Here, the authors generate a comprehensive map of accessible chromatin by integrating the ATAC-seq data of ...

Microglia, Pediatric Neurology, Autism Spectrum Disorder, Epilepsy, Neuroinflammation, Neurodevelopment Kaur, H. (2025) The ...

The second act of a popular reprogramming factor could maximize the potential of iPSCs in research and regenerative medicine.

A new study provides detailed insights into the embryogenesis and eye development of the cave-dwelling spider Tegenaria pagana. The research, published in EvoDevo, examines key genetic mechanisms ...

Embryos were fixed for 30 min at room temperature with 4% paraformaldehyde in MOPS buffer (0.1 M 3-(N-morpholino) propane sulfonic acid), adjusted to a pH value of 7.5, and washed in PBT two times.

Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan 430072, China University of Chinese Academy of Sciences, Beijing 100049, China Institute of Hydrobiology, Chinese Academy of Sciences, ...

Genetic disruption of nicotinamide adenine dinucleotide (NAD) de novo synthesis causes multiple malformations, collectively termed Congenital NAD Deficiency Disorder (CNDD), highlighting the necessity ...

At a minimum, the authors should perform in situ hybridization or immunostaining for Tdo2, Afmid, Kmo, Kynu, Haao, Qprt and Nadsyn1 or some combination thereof at multiple time points during early ...

This month's cover highlights the article Nup358 restricts ER-mitochondria connectivity by modulating mTORC2/Akt/GSK3β signalling by Joseph, Misha Kalarikkal and colleagues. The image shows a human ...

It has enabled us to make a clear distinction between smallEVs and largeEVs and demonstrate that at least two different types of EVs are involved in zebrafish embryogenesis." Another significant ...

This finding shows the limitation of using animals to study human embryogenesis and the importance of scientists having access to patient samples. "Inherited diseases are most prevalent in the ...