An analysis of an unusual enzyme could result in a new generation of antimicrobial medicines to counter antibiotic resistance. Key details in the enzyme-driven biosynthesis of a natural molecule with ...

Raw materials play a critical role in cell therapy manufacturing. Choosing suboptimal materials at any stage of development ...

A single enzyme that can generate all four nucleotide triphosphates, the building blocks of ribonucleic acid (RNA), was ...

Researchers identified a polyphosphate kinase that converts nucleotide precursors into all four RNA nucleotides in one step. Using inexpensive polyphosphate, the enzyme enables low-cost, efficient NTP ...

The development of new therapeutics targeting protein kinases is crucial in the fight against diseases like cancer.

Maintaining cellular order is a major logistical challenge: Individual mammalian cells contain billions of protein molecules, which must be synthesized, deployed, and removed with precision.

The enzyme E3 ligase plays a key role here by acting as a “broker” that mediates the labeling of the proteins to be degraded. A research team at Goethe University Frankfurt has now made the first ...

Enzymes help with specific functions that are vital to the operation and overall health of the human body. They help speed up chemical reactions and are essential for respiration, digestion, muscle ...