Among members of the Richardson family who carry a mutation in the PSEN1 gene, the average age when symptoms start is 39.

Cryptic mtDNA mutation is a predominant form of mutation and reaches physiologically relevant levels in later life. Credit: Nature Communications (2025). DOI: 10.1038/s41467-025-57286-8 ...

Mutations are rare boosts that can affect your crops during growth. While most crops in Grow a Garden grow in their default state, certain factors like weather, game events, or specific equipment ...

Most people know that inherited traits between generations is a genetic process, but a new study says other inheritable mechanisms may exist. Scientists at the University of Toronto studying the ...

In a subset of Alzheimer’s disease patients, non-inheritable mutations that activate a population of brain cells known as microglia may contribute to dementia. Open annotations (there are currently 0 ...

Key Takeaways KRAS G12D and G12V mutations in pancreatic ductal adenocarcinoma are associated with worse outcomes compared to KRAS wild-type. KRAS G12R mutation is linked to more favorable patient ...

Mutation clearance did not appear to be affected by the presence of TP53 mutations; mutation clearance at day 30 after transplantation was found in 9 patients (47%) with TP53 mutations and 152 ...

BRCA mutations are inextricably linked with breasts, but they can also lead to cancer in the pancreas, the prostate, and maybe more parts of the body.

Drug addiction mutations lead to some of the cancer cells using the drug to help them grow, instead of destroying them. For these types of mutations the study results support the use of “drug ...

In a study published in the journal Nature, researchers from the Center for Genomic Regulation (CRG) and the Wellcome Sanger Institute have discovered that mutations affect protein stability ...

A common mutation on BRCA1 or BRCA2 genes is highly inheritable in families. Fathers can also pass it to daughters. Having the mutation raises the chances of women getting breast cancer to about ...

Imatinib resistance in GI stromal tumors (GISTs) is primarily caused by secondary KIT mutations, and clonal heterogeneity of these secondary mutations represents a major treatment obstacle. KIT ...