2024 was a promising year for running back Isaac Guerendo. He filled in nicely when both Christian McCaffrey and Jordan Mason were injured. It seemed like the San Francisco 49ers finally nailed a ...

Guerendo ran back one kickoff for 18 yards while receiving no carries or targets in Thursday's 26-23 overtime win over the Rams. Christian McCaffrey continued to operate as San Francisco's bell cow ...

Guerendo did not receive a carry while gaining 19 yards on a kickoff return in Sunday's 16-15 win over the Cardinals. Guerendo continued to be used exclusively on special teams, logging all 15 of his ...

The San Francisco 49ers‘ running-back room is as strong as it has been in some time. With 2023 NFL Offensive Player of the Year Christian McCaffrey, the acquisition of Brian Robinson Jr. from the ...

As a young, pass-catching running back in the NFL, perhaps there’s no one better to learn from than Christian McCaffrey. That’s especially true if the All-Pro happens to be your teammate, like in ...

LB Tatum Bethune and RB Isaac Guerendo spoke on their personal growth entering their second NFL season, the impact of veteran mentorship, and how refining technique, nutrition, and film study has ...

Amid a handful of injuries in their running back room, the San Francisco 49ers are bolstering their backfield. Per ESPN's Adam Schefter, the 49ers are re-signing running back Jeff Wilson, who ...

The 49ers are going to be down a couple of players for the near future. Head coach Kyle Shanahan told reporters at a Monday press conference that running back Isaac Guerendo is going to miss a couple ...

SANTA CLARA — Running back Isaac Guerendo and fullback Kyle Juszczyk each left Saturday’s practice after sustaining injuries, with no preliminary word from the 49ers on the severity of either.