Isaac Guerendo: High School Star's Solid Foundation to San Francisco 49ers Standout. Isaac Guerendo grew up in Avon, Indiana, just outside Indianapolis in a family that has always played a pivotal ...

Isaac Guerendo made an impression during his 2024 rookie campaign, ... "Obviously, he's one of the greatest backs," Guerendo said in April 2024. "I was just telling my family, ...

Isaac Guerendo grew up in Avon, Indiana, just outside Indianapolis in a family that has always played a pivotal role in his development, both on and off the field.