For one, microglia hovering around plaques—the type that express the most TREM2—reportedly become desensitized to stimulation ...

Examples of organelles include the nucleus, the endoplasmic reticulum, the Golgi, mitochondria, vacuoles or lysosomes, and chloroplasts (in plants). A new study reveals a surprising mechanism by ...

The NEET UG syllabus includes Physics, Chemistry and Biology (Botany and Zoology). Candidates can download the latest NEET ...

The researchers measured nearly 40 percent less LAMP2, LIMP-2, GCase, and cathepsin B in the knockout cell lysosomes. These cells also cleaved prosaposin and progranulin less effectively. Progranulin ...

A recent study reveals that regular cold water swimming can positively alter cellular stress responses. Immersing healthy young men in cold water dail ...

The biotech is focusing on precision, small-molecule medicines that work via a process known as cellular clearance by activating the lysosome, sometimes referred to as the cell’s recycling and ...

In this guide, we’ll explain the OKR framework and when OKRs should be used. We’ll also provide several examples of objectives and key results so that you can better understand how to ...

The Farese & Walther laboratory investigates cellular lipid and energy metabolism, in particular the mechanisms and physiology of neutral lipid synthesis and storage in lipid droplets. More broadly ...

A University of Alberta study shows that rural Albertans living with multiple sclerosis are not as likely as urban patients to receive the best treatments to prevent relapses and slow down ...

ADCs in Preclinical Development for the Treatment of B-cell Malignancies With the evolving clinical data demonstrating the feasibility of the ADC platform in hematologic malignancies, the ...

Figure 1: Representative images of the induction of autophagy and the outcome of its suppression. Figure 2: The role of autophagy in development and differentiation in mammals.