A study maps how toxic tau disrupts synapses over time, showing early postsynaptic damage that later spreads presynaptically.

ORLANDO, Fla. — Already one of the nation’s busiest airports, record travel demand is pushing Orlando International Airport (MCO) to undertake major upgrade and renovation projects. Experts say the ...

A holistic inquiry into how toxic tau impacts synapses provides a new take on the processes that lead to neuronal dysfunction ...

A holistic inquiry into how toxic tau impacts synapses provides a new take on the processes that lead to neuronal dysfunction and memory loss in Alzheimer's disease. A tool, developed in the Tracy lab ...

Summary: Scientists have uncovered a key role for the protein “Frazzled” in building and maintaining the rapid neural connections that allow fruit flies to react in milliseconds. When Frazzled is ...

Elizabeth Jonas first got interested in mitochondria by chance. In 1995, she was a postdoctoral researcher at Yale, working at the Marine Biological Lab in Woods Hole, Massachusetts, where she was ...

Optical tracers in conjunction with fluorescence microscopy have become widely used to follow the movement of synaptic vesicles in nerve terminals. The present review discusses the use of these ...

At 15 years old, Sammy considered himself an expert on cannabis. When I asked what he knew about how marijuana interacts with the brain, he confidently explained, “THC activates cannabinoid receptors ...

The replenishment of synaptic vesicles (SVs) to the active zone (AZ) at presynaptic terminals is required to sustain neurotransmitter release in response to high levels of neuronal activity. Despite ...