Strength-in-numbers X-ray technique can map previously unattainable atomic structures

For many decades, the method to obtain atomic-level descriptions of chemical compounds and materials—be it a drug, a catalyst ...
EurekAlert!

Engineering a rigid protein ruler to measure antibody flexibility

A research team engineered a rigid, nanometer-scale protein module to address the challenge of measuring antibody flexibility ...
Interesting Engineering

AlphaFold and the architecture that cracked protein structure

Artificial intelligence isn’t just changing how we search the web or generate images. It is reshaping how scientists approach one of biology’s oldest problems: the folding of proteins. Google DeepMind ...
C&EN

Demonstration of Advanced Timing Schemes in Time-Resolved X-ray Diffraction Measurements

Article subjects are automatically applied from the ACS Subject Taxonomy and describe the scientific concepts and themes of the article. Consider now a different scheme for time-resolved measurements ...
Medicine Buffalo

Structural Studies of Metalloproteins from Bacterial Pathogens

Antibacterial resistance is responsible for nearly 1.3 million deaths globally each year; these numbers are projected to rapidly increase to nearly 10 million annually by 2050. As the growing threat ...
9to5Mac

Apple researchers develop SimpleFold, a lightweight AI for protein folding prediction

Google DeepMind’s work with AlphaFold has been nothing short of a miracle, but it is computationally expensive. With that in mind, Apple researchers set off to develop an alternative method to use AI ...
IEEE

Enhancing Protein Structure Learning using a Size-Guided Conditional Mixture-of-Experts

Abstract: In recent years, deep learning on protein structures has attracted widespread attention, as structures determine proteins' function. A series of structure-based protein property prediction ...
GEN

Protein Language Model Hits Undruggable Targets, No Structure Required

Pranam Chatterjee, PhD, assistant professor of bioengineering at the University of Pennsylvania (UPenn), emphasizes that text is all you need for artificial intelligence (AI) models to effectively ...
News Medical

Researchers map atomic structure of protein complex driving cilia movement

A team led by UT Southwestern Medical Center researchers has uncovered the atomic structure of a protein complex pivotal to the function of motile cilia, the hair-like structures extending from the ...
IEEE

A Denoising Method for X-Ray Ptychography Combining a Physical Diffraction Model With a Deep Image Prior Network

Abstract: X-ray ptychography is a lensless imaging technology with promising applications that can achieve nanometer resolution. However, the noise in the diffraction patterns degrades the performance ...
News Medical

Scientists unveil dynamic structure of protein key to vision

Scientists have for the first time looked deep into the protein structure that may determine our vision - and discovered that it is much more dynamic than previously thought. RBP3 not only changes its ...