1Molecular Pharmacology of Malignant Diseases, Graduate School of Pharmaceutical Sciences, ...
1Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, ...
Defining the Antitumor Mechanism of Action of a Clinical-stage Compound as a Selective Degrader of the Nuclear Pore Complex Open Access Linjie Yuan; Wenzhi Ji; Brendan G. Dwyer; Joey Lu; Jing Bian; ...
Abstract. Antibody-drug conjugates (ADCs) enable the specific targeting of a potent cytotoxic drug to cancer cells expressing a select antigen via the release of the cytotoxin covalently linked to a ...
Cancer Res (2026) 86 (7_Supplement): 5810.
Although some patients with cervical cancer respond well to therapy, others show minimal response and develop recurrence after treatment. A better understanding of the molecular features that ...
Abstract. Breast cancers with high expression of estrogen receptor (ER), progesterone receptor (PR), or Human Epidermal Growth Factor Receptor 2 (HER2) have benefited dramatically from ...
Abstract. Targeting ligands play a critical role in radiopharmaceuticals for cancer diagnosis and therapy. Due to their excellent binding affinity and specificity, peptides have been widely used to ...