Systolic time intervals and drug plasma concentrations have been measured in a group of patients receiving repeated treatment with nortriptyline. Significant positive correlations between plasma ...

Correspondence to Dr James Philip Howard, National Heart and Lung Institute, Imperial College London, London W12 0NN, UK; research{at}cardiologists.london Understand the paradigm of machine learning.

Background The Assessing cardiovascular risk using Scottish Intercollegiate Guidelines Network (ASSIGN) risk score, developed in 2006, is used in Scotland for estimating the 10-year risk of first ...

Background Cardiopulmonary exercise testing (CPET) is essential for assessing patients with hypertrophic cardiomyopathy (HCM) ...

Vascular endothelial growth factor inhibitors (VEGFIs) have transformed treatment paradigms for several malignancies. By ...

All pilots in the USA must undergo medical certification by an aeromedical examiner (AME) at regular intervals. The Federal ...

Correspondence to Professor Richard J McManus, Nuffield Department of Primary Care Health Sciences, Radcliffe Observatory Quarter, University of Oxford, Oxford OX2 6GG, UK; ...

Background The relationship between objectively measured hearing ability and the risk of incident heart failure (HF) remains unclear. This study aimed to assess this association, explore potential ...

Objective: To assess whether use of oral glucocorticoids is associated with cardiovascular and cerebrovascular morbidity. Design and setting: Nested case–control study within a cohort of patients (⩾ ...

Background Apical hypertrophic cardiomyopathy (HCM) is a rare variant of HCM, often considered to have a benign prognosis. This study aimed to compare the clinical characteristics and genetic ...

Correspondence to Professor Alec Vahanian, Department of Cardiology, Hôpital Bichat, Huchard, 75018 Paris, France; alec.vahanian{at}bch.aphp.fr In current practice, the use of TSP has shifted from a ...