A new weight loss drug target may help reduce appetite and burn calories without causing sickness, research suggests. The discovery could lead to a new treatment for millions of people with both ...

Sara Sharif’s father has confessed to killing the 10-year-old but insisted he did not mean to “harm” her when he bound and beat her with a cricket bat. Taxi driver Urfan Sharif, 42, had sought to ...

Sixteen people suffered minor injuries after a lorry and bus carrying schoolchildren collided in Leicestershire. The bus and the HGV crashed on the A46 northbound near to Syston at around 9.30am on ...

A woman who was with Nikita Hand in the hotel where she claims she was raped by Irish mixed martial arts fighter Conor McGregor, has told a High Court she was “surprised” to learn of the alleged ...

Sir Keir Starmer has said he was expecting to see Nigel Farage included in America’s immigration statistics, as he joked that the Reform UK leader was making a “rare appearance in Britain”.

Kevin says: “When a business enters administration, they do tend to operate as normal whilst they wind down the business - however if acquired, it could mean Homebase won’t have to fulfil any existing ...

Sir Keir Starmer resisted pressure from an Independent MP during Prime Minister’s Questions to describe the war in Gaza as “genocide”. When asked for his definition of the word, Sir Keir told the ...

Planning for a “smooth transition” at the Grangemouth refinery should have started five years ago, MSPs have been told. Representatives of Petroineos, which owns the Scottish plant and has announced ...

Screams of horror could be heard as a man killed his friend at their home in Wales on Christmas Eve, a court has heard. Dylan Thomas, 24, is accused of murdering William Bush, 23, who died on December ...

Spy-accused former soldier Daniel Khalife had a 30-minute phone conversation with an Iranian agent while posted at a US army base, a court has heard. The three calls “rekindled” Iran’s interest in ...

Mr Scholz declared his plans for the vote of confidence one week after his three-party coalition government collapsed.

ITV is to air Coleen Rooney: The Real Wagatha Story, a documentary about her libel case with Rebekah Vardy, ahead of the 38-year-old’s first appearance on I’m A Celebrity… Get Me Out Of Here! this ...