NF-κB waits for activation in the cytosol, complexed with the inhibitory protein IκBα. Various extracellular signals can enter the cell via membrane receptors and activate the enzyme IκB kinase (IKK).

Jul 24, 2025 · Nuclear Factor kappa-light-chain-enhancer of activated B cells, commonly known as NF-κB, is a family of protein complexes that act as transcription factors. These complexes control DNA …

Jul 14, 2017 · The transcription factor NF-κB regulates multiple aspects of innate and adaptive immune functions and serves as a pivotal mediator of inflammatory responses.

2 days ago · These proteins function as dimeric transcription factors that regulate the expression of genes influencing a broad range of biological processes including innate and adaptive immunity, …

Sep 30, 2025 · Nuclear Factor Kappa-Light-Chain-Enhancer of Activated B Cells (NF-κB): a group of proteins that act as transcription factors for different cellular functions, including immune response, …

NF-kB is a transcription factor that plays a critical role in normal physiology and bladder cancer. Bladder cancer patients have pathologically active NF-kB induced by proinflammatory cytokines, …

NF-κB (Nuclear Factor kappa-light-chain-enhancer of activated B cells) is a protein complex that plays a crucial role in regulating immune response, cell survival, and inflammation.

Also called NF-kappa B and nuclear factor-kappa B. A group of proteins that help control many functions in a cell, including cell growth and survival. These proteins also control the body’s immune and …

Nov 30, 2023 · NF-κB (nuclear factor kappa light chain enhancer of activated B cells) is a family of highly conserved transcription factors that regulate many important cellular behaviours, in particular, …

We shall see later in this section that although the protein is always called NF-kB, it is a group of related homodimeric and heterodimeric transcription factors that are likely to activate distinct sets of target …